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Adaptive diagnostic reasoning framework for pathology with multimodal large language models

Yunqi Hong, Kuei-Chun Kao, Liam Edwards, Nein-Tzu Liu, Chung-Yen Huang, Alex Oliveira-Kowaleski, Cho-Jui Hsieh* & Neil Y. C. Lin* 

Communications Medicine, 6, 236 (2026) PDF

Uncertainty-Guided Selective Adaptation Enables Cross-Platform Predictive Fluorescence Microscopy

Kai-Wen K Yang, Andrew Bai, Alexandra Bermudez, Yunqi Hong, Zoe Latham, Iris Sloan, Michael Liu, Vishrut Goyal, Cho-Jui Hsieh*, Neil YC Lin*

Advanced Intelligent Discovery, (2026) PDF

Regulation of Chromatin Modifications through Coordination of Nucleus Size and Epithelial Cell Morphology Heterogeneity

Alexandra Bermudez, Zoe Latham, Alex Ma, Dapeng Bi, Jimmy Hu*, Neil Y.C. Lin*

Communications Biology, 8, 269 (2025) PDF

Nucleo-Cytoskeletal Coupling Controls Intracellular Deformation Partitioning during Cell Stretching

Jerry Chen, Iris Sloan, Alexandra Bermudez, David Choi, Ming-Heng Tsai, Lihua Jin, Jimmy Hu*, Neil Y.C. Lin*

Royal Society Open Science, 12: 250409 (2025) PDF

Large-scale acoustic single cell trapping and selective releasing

Xiang Zhang, Jacob Smith, Amanda Chengyi Zhou, Jacqueline Thuy-Tram Duong, Tong Qi, Shilin Chen, Yen-Ju Lin, Alexi Gill, Chih-Hui Lo, Neil Y. C. Lin, Jing Wen, Yunfeng Lu, and Pei-Yu Chiou*

Lab on a Chip, 25, 1537-1551 (2025) PDF

What causes calcium oxalate kidney stones to form? An update on recent advances

Reyhaneh Nazarian, Neil Lin, Sapna Thaker, Rena Yang, Gerard CL Wong, Kymora B Scotland*

Uro, 5, 6 (2025) PDF

Regulation of Epithelial Cell Jamming Transition by Cytoskeleton and Cell-Cell Interactions

Zoe Latham, Alexandra Bermudez, Jimmy Hu*, Neil Y.C. Lin*

Biophysics Reviews, 5, 041301 (2024) PDF

An Open-Source Membrane Stretcher for Simultaneous Mechanical and Structural Characterizations of Soft Materials and Biological Tissues, Shannon Li, Alyssa Gee, Nathan Cai, Alexandra Bermudez, Neil Y.C. Lin*

HardwareX, 19, e00552 (2024) PDF

Prostate lineage-specific metabolism governs luminal differentiation and response to antiandrogen treatment, Giafaglione, J.M., Crowell, P.D., Delcourt, A.M.L., ... Payne M.C,, ... Lin N.Y.C, ... Goldstein A.S.

Nature Cell Biology, 1476-4679 (2023) PDF

Using Histologic Image Analysis to Understand Biophysical Regulations of Epithelial Cell Morphology 

Alexandra Bermudez, Samanta Negrete Muñoz, Rita Blaik, Amy C. Rowat, Jimmy Hu*, Neil Y.C. Lin*

Biophysicist, 4, 2 (2023) PDF

Trustworthy in silico Cell Labeling via Ensemble-based Image Translation

Sara Imboden, Xuanqing Liu, Marie C. Payne, Cho-Jui Hsieh, and Neil Y. C. Lin*

Biophysical Reports, 4, 100133 (2023) PDF 

Phenotyping Senescent Mesenchymal Stromal Cells using AI Image Translation

Leya Weber+, Brandon Lee+, Sara Imboden, Cho-Jui Hsieh, and Neil Y.C. Lin*

Current Research in Biotechnology, 5, 100120 (2023) PDF

Concept Gradients: Concept-Based Interpretation without Linear Assumption 

Andrew Bai, Chih-Kuan Yeh, Neil Y. C. Lin, Pradeep Ravikumar, Cho-Jui Hsieh

International Conference on Learning Representation (ICLR) (2023) PDF

Microwell-Based Flow Culture Increases Viability and Restores Drug Response in Prostate Cancer Spheroids

Marie C. Payne, SumYat Ho, Takao Hashimoto, Sara Imboden, Johnny A. Diaz, Brandon S. Lee, Melissa J. Rupert, Nathan Y. Cai, Andrew S. Goldstein, and Neil Y.C. Lin

Biotechnology Journal, 2200434 (2023) Featured on Journal Front Cover PDF

Rapid prototyping of functional acoustic devices using laser manufacturing

Xiang Zhang, Rosa Son, Yen-Ju Lin, Alexi Gill, Shilin Chen, Tong Qi, David Choi, Jing Wen, Yunfeng Lu, Neil YC Lin, and Pei-Yu Chiou

Lab on a Chip, 22, 4327 (2022) PDF

Supracellular Measurement of Spatially Varying Mechanical Heterogeneities in Live Monolayers
Alexandra Bermudez, Zachary Gonzalez, Bao Zhao, Ethan Salter, Xuanqing Liu, Leixin Ma, Mohammad Khalid Jawed, Cho-Jui Hsieh, and Neil Y.C. Lin 

Biophysical Journal, 121(18), 3358-3369 (2022) PDF

Cell-cell Adhesion Impacts Epithelia Response to Substrate Stiffness: Morphology and Gene Expression,

David Choi, Zachary Gonzalez, Sum Yat Ho, Alexandra Bermudez, and Neil Y.C. Lin

Biophysical Journal, 121(2), 336-346 (2022) PDF

Investigating Heterogeneities of Live Mesenchymal Stromal Cells Using AI-Based Label-Free Imaging

Sara Imboden, Xuanqing Liu, Brandon S. Lee, Marie C. Payne, Cho-Jui Hsieh, and Neil YC Lin.

Scientific Report 11, no. 1 (2021): 1-11. PDF

Biotechnology Journal - 2023 -  - Outside Front Cover   Biotechnology Journal 6 2023.jpg
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